Title:
線維症を処置するためのc-kit阻害剤の使用法
Document Type and Number:
Japanese Patent JP2007533732
Kind Code:
A
Abstract:
The present invention relates to a method for treating fibrosis and related disorders comprising administering a compound capable of depleting mast cell or a compound inhibiting mast cells degranulation, to a human in need of such treatment. Such compounds can be chosen from c-kit inhibitors and more particularly non-toxic, selective and potent c-kit inhibitors. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.
Inventors:
Mousie Alan
Kinet Gene-Pierre
Kinet Gene-Pierre
Application Number:
JP2007509011A
Publication Date:
November 22, 2007
Filing Date:
April 19, 2005
Export Citation:
Assignee:
Ab science
International Classes:
A61K45/00; A61K31/4178; A61K31/421; A61K31/426; A61K31/427; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61K31/496; A61K31/497; A61K31/506; A61K31/517; A61K31/5355; A61K31/5377; A61P1/16; A61P1/18; A61P9/10; A61P9/14; A61P11/00; A61P13/12; A61P15/08; A61P17/00; A61P43/00; C07D263/48; G01N33/15; G01N33/50; C07D277/20; C07D277/42; C07D277/56; C07D401/04; C07D413/04; C07D413/12; C07D413/14; C07D417/04; C07D417/14
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi