Title:
ヒトＦＧＦＲ２Ｂ細胞外ドメイン及びそれをコードする核酸
Document Type and Number:
Japanese Patent JP6408603
Kind Code:
B2
Abstract:
Provided are wild-type, S252W mutant-type, and P253R mutant-type FGFR2b extracellular segments and truncated proteins thereof, coding genes of the foregoing proteins, a recombinant vector comprising the genes, a host cell, a method for preparing the proteins, and a fusion protein of the proteins and an Fc segment. Also provided are applications of the proteins and a composition comprising the proteins in treating eczema, acne, psoriasis, skin allergy, seborrheic dermatitis, or seborrheic alopecia.
Inventors:
Warne Juy
Wan Yi
Wan Yi
Application Number:
JP2016559488A
Publication Date:
October 17, 2018
Filing Date:
December 19, 2014
Export Citation:
Assignee:
Gwan Zhou Shuyongru Biotech Limited Company
International Classes:
C12N15/13; A61K31/7105; A61K31/713; A61K35/12; A61K35/64; A61K35/74; A61K36/062; A61K38/17; A61K39/395; A61K45/00; A61K48/00; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P17/08; A61P17/14; A61P37/08; C07K14/715; C07K19/00; C12N1/19; C12N1/21; C12N5/10
Foreign References:
| WO2009101199A1 |
Other References:
Biochem. J.,2011年 6月28日,Vol. 437,p. 199-213
Journal of Investigative Dermatology,2009年,Vol. 129, Issue 8,p. 1868-1877
Mol Cance Ther,2011年 9月,Vol. 10, No. 9,p. 1656-1666
Journal of Investigative Dermatology,2009年,Vol. 129, Issue 8,p. 1868-1877
Mol Cance Ther,2011年 9月,Vol. 10, No. 9,p. 1656-1666
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei