Title:
インフルエンザヘマグルチニンに対するヒト抗体
Document Type and Number:
Japanese Patent JP7372925
Kind Code:
B2
Abstract:
The present invention provides monoclonal antibodies, or antigen-binding fragments thereof, that bind to the influenza hemagglutinin (HA) protein, pharmaceutical compositions comprising the antibodies and methods of use. The antibodies of the invention are useful for inhibiting or neutralizing influenza virus activity, thus providing a means of treating or preventing influenza infection in humans. In some embodiments, the invention provides for use of one or more antibodies that bind to the influenza HA for preventing viral attachment and/or entry into host cells. The antibodies of the invention may be used prophylactically or therapeutically and may be used alone or in combination with one or more other anti-viral agents or vaccines.
Inventors:
Purcell, Lisa A.
Biau, Jonathan
Olson, William
Biau, Jonathan
Olson, William
Application Number:
JP2020539709A
Publication Date:
November 01, 2023
Filing Date:
January 24, 2019
Export Citation:
Assignee:
REGENERON PHARMACEUTICALS, INC.
International Classes:
C12N15/13; A61K31/215; A61K39/395; A61P31/16; A61P43/00; C07K16/10; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63
Domestic Patent References:
| JP2016516090A |
Foreign References:
| WO2015051010A1 | ||||
| WO2016164835A1 | ||||
| WO2015120097A2 | ||||
| WO2017192589A1 | ||||
| WO2010073647A1 |
Other References:
SCIENCE,2011年,Vol.333,p.843-850 & Supporting Online Material
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Natsuki Morishita