To obtain a polynucleotide molecule useful for the diagnosis and treatment of tumors, autoimmune diseases, etc., by encoding a specific tumor antigenic peptide.

This polynucleotide molecule is selected from the group consisting of (i) a polynucleotide molecule encoding an amino acid sequence represented by the formula, (ii) a polynucleotide molecule encoding a protein in which one or plural amino acids are substituted, deleted, inserted or added in the amino acid sequence represented by the formula, (iii) a polynucleotide molecule comprising a base sequence represented by the formula, (iv) a polynucleotide molecule in which one or plural bases are substituted, deleted, inserted or added in the base sequence represented by the formula and (v) a polynucleotide molecule hybridizable with any of the polynucleotide molecule under stringent conditions. A peptide comprising a part of the protein encoded with the polynucleotide molecule is a tumor antigenic peptide bound to a main histocompatibility gene complex(MHC) class I antigen and recognized with a T cell.