Title:
ヒト細胞接着性タンパク質AAMP‐1及びその利用
Document Type and Number:
Japanese Patent JP3715313
Kind Code:
B2
Abstract:
The present invention relates, in general, to AAMP-1, and to a peptide derived from the amino-terminal region of AAMP, P189. In particular, the present invention relates to a DNA segment encoding AAMP-1, P189 or fragments thereof; polypeptides encoded by said DNA segment; recombinant DNA molecules containing the DNA segment; cells containing the recombinant DNA molecule; a method of producing a AAMP-1, and P189 polypeptide or fragments thereof; antibodies specific to AAMP-1; and a method of measuring the amount of AAMP-1 in a sample. The present invention further relates to methods of using AAMP, P189 or fragments thereof in promoting cell-cell or cell-substrate adhesion, wound healing in patients, prosthetic acceptance, concentrating heparin in tissues, and inhibiting metastases and invasion of malignant cells.
Inventors:
Beckner, Marie E.
Kursh, Henry See.
Riotta, Lance A.
Kursh, Henry See.
Riotta, Lance A.
Application Number:
JP50308595A
Publication Date:
November 09, 2005
Filing Date:
June 23, 1994
Export Citation:
Assignee:
THE UNITED STATES OF AMERICA
International Classes:
G01N33/569; A61K38/00; A61K39/395; A61P29/00; A61P35/00; A61P37/00; A61P43/00; C07H21/04; C07K7/06; C07K7/08; C07K14/16; C07K14/705; C07K14/74; C07K14/78; C07K16/00; C07K16/18; C07K16/28; C12N1/21; C12N5/10; C12N15/02; C12N15/09; C12N15/12; C12P21/02; C12P21/08; G01N33/566; G01N33/577; G01N33/68; C12R1/19; (IPC1-7): C12N15/09; C07K7/08; C07K14/78; C12N5/10
Domestic Patent References:
| JP7505051A |
Attorney, Agent or Firm:
Takashi Ishida
Yoshio Yoshio
Masaya Nishiyama
Yoshio Yoshio
Masaya Nishiyama