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Title:
HUMAN INTERLEUKIN-2 PROTEIN AND ITS PRODUCTION
Document Type and Number:
Japanese Patent JP2555816
Kind Code:
B2
Abstract:

PURPOSE: To produce the substantially pure non-glycosylated human interleukin-2 protein.
CONSTITUTION: The substantially pure non-glycosylated human interleukin-2 protein which is obtained by the culture of a transformed Escherichia coli and which has a specific activity of ≥104 U/mg. The protein can safely be used as a raw material for injection medicines because of being extremely reduced in the contents of contaminated proteins and pyrogens.


Inventors:
KATO KOICHI
YAMADA TAKAHISA
ONDA HARUO
Application Number:
JP29334991A
Publication Date:
November 20, 1996
Filing Date:
November 08, 1991
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
A61K38/00; A61P35/00; A61P37/04; C07K14/00; C07K14/52; C07K14/54; C07K14/55; C12N15/09; C12N15/26; C12P21/02; C12R1/19; (IPC1-7): C07K14/55; C12N15/09; C12P21/02
Domestic Patent References:
JP5970620A
JP6012986A
Other References:
【文献】欧州特許91539(EP,A)
Attorney, Agent or Firm:
Tadao Asahina (2 outside)