Title:
HUMAN NEUREGULIN-1 (NRG-1) RECOMBINANT FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
Document Type and Number:
Japanese Patent JP2023134436
Kind Code:
A
Abstract:
To provide human neuregulin-1 (NRG-1) recombinant fusion protein compositions and use methods thereof.SOLUTION: The present invention relates to a recombinant fusion protein comprising a fragment of the cardioprotective protein neuregulin-1 (NRG-1) fused to a monoclonal antibody (mAb) backbone and to a method of treating a disease or condition in a subject in need thereof comprising administering a therapeutically effective amount of the recombinant fusion protein or a pharmaceutical composition comprising the recombinant fusion protein disclosed herein.SELECTED DRAWING: Figure 2A-B
Inventors:
HUA LIANG
LUO PENGYI
WANG YAN
LEE JOHN
LI SHENGWEI
LUO DIXIANG
WU YIRAN
CHO MIN
ZHUANG XIAOLEI
LUO PENGYI
WANG YAN
LEE JOHN
LI SHENGWEI
LUO DIXIANG
WU YIRAN
CHO MIN
ZHUANG XIAOLEI
Application Number:
JP2023097663A
Publication Date:
September 27, 2023
Filing Date:
June 14, 2023
Export Citation:
Assignee:
SALUBRIS BIOTHERAPEUTICS INC
SALUBRIS CHENGDU BIOTECH CO LTD
SALUBRIS CHENGDU BIOTECH CO LTD
International Classes:
C12N15/62; A61K39/395; A61P9/00; A61P9/04; C07K14/475; C07K16/30; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12N15/13; C12N15/63
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Michiko Uehara
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Michiko Uehara