Title:
外因性ポリペプチドを発現するヒト皮膚同等物
Document Type and Number:
Japanese Patent JP4993752
Kind Code:
B2
Abstract:
The present invention relates generally to compositions for wound healing. More specifically, the present invention provides human skin equivalents engineered to express exogenous proteinase inhibitor polypeptides (e.g., TIMP-1 polypeptides) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
Inventors:
Allen-Hoffman Lynn
Iberly Kathy Ann-Rasmussen
Thomas-Billing Christina Elle.
Iberly Kathy Ann-Rasmussen
Thomas-Billing Christina Elle.
Application Number:
JP2007558185A
Publication Date:
August 08, 2012
Filing Date:
March 01, 2006
Export Citation:
Assignee:
Stratatech Corporation
International Classes:
A61K35/12; A61K48/00; A61L27/00; A61P1/04; A61P9/00; A61P17/02; A61P43/00; C12N5/071; C12N15/09
Foreign References:
| WO2003093418A1 | ||||
| WO2005012492A1 |
Other References:
Cell and Tissue Research,2004年,Vol.315,pp.27-37
Gene Therapy,1999年,Vol.6,pp.1734-1741
Proceedings of the National Academy of Sciences of the United States of America,1994年,Vol.91,pp.9307-9311
Gene Therapy,1999年,Vol.6,pp.1734-1741
Proceedings of the National Academy of Sciences of the United States of America,1994年,Vol.91,pp.9307-9311
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue