Title:
白血球付着分子VLA-4に対するヒト化抗体
Document Type and Number:
Japanese Patent JP5487382
Kind Code:
B2
Abstract:
The invention provides humanized immunoglobulins that specifically bind to the VLA-4 ligand, and methods of treatment using the same. The methods are particularly useful for the treatment of multiple sclerosis.
Inventors:
Mary M. Beding
Olivier Jay Léger
Jose Saldanha
Thalang S. Jones
Olivier Jay Léger
Jose Saldanha
Thalang S. Jones
Application Number:
JP2013028635A
Publication Date:
May 07, 2014
Filing Date:
February 18, 2013
Export Citation:
Assignee:
Biogen Idec MA Inc.
International Classes:
C07K16/28; G01N33/53; A61K39/395; A61P7/00; A61P29/00; A61P37/00; C07H21/04; C07K16/18; C07K16/46; C12N5/00; C12N5/10; C12N15/09; C12N15/13; C12P21/08; A61K38/00; A61P25/00; C12R1/91; C07K
Domestic Patent References:
| JP4502408A |
Foreign References:
| WO1993015764A1 |
Other References:
Agents Actions, 1993, Vol.39 (Special Confernece Issue), p.C177-C179
Protein Engineering, 1991, Vol.4, No.7, p.773-783,P773-777,780-783
Protein Engineering, 1993, Vol.6, No.8, p.971-980
Protein Engineering, 1991, Vol.4, No.7, p.773-783,P773-777,780-783
Protein Engineering, 1993, Vol.6, No.8, p.971-980
Attorney, Agent or Firm:
Takeshi Oshio