Title:
ハイブリッドオピオイド化合物および組成物
Document Type and Number:
Japanese Patent JP2014508148
Kind Code:
A
Abstract:
Disclosed are hybrid opioid compounds, mixed opioid salts, compositions comprising the hybrid opioid compounds and mixed opioid salts, and methods of use thereof. More particularly, in one aspect the hybrid opioid compound includes at least two opioid compounds that are covalently bonded to a linker moiety. In another aspect, the hybrid opioid compound relates to mixed opioid salts comprising at least two different opioid compounds or an opioid compound and a different active agent. Also disclosed are pharmaceutical compositions, as well as to methods of treating pain in humans using the hybrid compounds and mixed opioid salts.
Inventors:
Holladay, John W..
Majistro, philip
Majistro, philip
Application Number:
JP2013553565A
Publication Date:
April 03, 2014
Filing Date:
February 09, 2012
Export Citation:
Assignee:
QR Pharma Limited
International Classes:
A61K47/48; A61K31/485; A61K47/22; A61P25/04; A61P25/24
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto