Title:
HYBRIDOMA SECRETING MONOCLONAL ANTIBODY AGAINST CANCER PROTEIN
Document Type and Number:
Japanese Patent JP2592581
Kind Code:
B2
Abstract:
PURPOSE: To provide the subject hybridoma useful for the high-yield production of a monoclonal receptor capable of estimating the presence of a cancer protein from a body specimen obtained by a non-invasive means.
CONSTITUTION: The objective hybridoma is a hybridoma (ATCC HB 85938596) secreting a receptor molecule (κ-light chain, IgGI monoclonal receptor) produced against an immunogen SDVWSFGILLWETFSLGASPYPNLSNQQTR Containing a receptor molecule formed against an immunogen containing (a) a polypeptide SPYPNLSNQQTR corresponding to a part of the amino acid residue sequence of (b) a protein ligand (p89 cancer protein coded by the v-fes gene of ST-FeSV) coded by a retrovirus gene and bonding to both of the protein ligand (b) and the polypeptide (a). The hybridoma can be produced by conventional method described by Kohler and Milstein.
Inventors:
NIIMAN HENRII ERU
RAANAA RICHAADO AREN
RAANAA RICHAADO AREN
Application Number:
JP25363394A
Publication Date:
March 19, 1997
Filing Date:
October 19, 1994
Export Citation:
Assignee:
SCRIPPS CLINIC RES
International Classes:
A61K39/00; A61K39/395; A61P31/12; A61P35/00; B01J20/22; C07K1/22; C07K7/08; C07K14/005; C07K14/15; C07K14/195; C07K14/41; G01N33/574; C07K14/52; C07K14/705; C07K14/82; C07K16/00; C07K16/32; C07K19/00; C12N5/00; C12N5/10; C12N15/00; C12N15/02; C12P21/00; C12P21/08; G01N33/577; C12R1/91; (IPC1-7): C12N5/10; C12P21/08; G01N33/574; G01N33/577
Domestic Patent References:
| JP59113898A |
Other References:
ＰＲＯＣ．ＮＡＴＬ．ＡＣＡＤ．ＳＣＩ．ＵＳＡ，８０（５），１２４６−１２５０（１９８３）
Attorney, Agent or Firm:
Minoru Nakamura (2 outside)