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Title:
HYDROCHLORIDE OF ANTIBIOTIC COMPOUND
Document Type and Number:
Japanese Patent JP2018177817
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide hydrochloride of an antibiotic compound.SOLUTION: The present invention relates to a compound of formula I. Such compounds are acid addition salts of hydrochloric acid and 26-[[[3-[[(Z)-[1-(2-amino-5-chloro-4-thiazolyl)-2-[[(6R,7R)-2-carboxy-8-oxo-3-(pyridiniomethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl]amino]-2-oxoethylidene]amino]oxy]propyl]amino]-carbonyl]-26-decarboxyvancomycin. In the compounds of formula I, any atom capable of being protonated by the hydrochloric acid (such as an amino group or carboxylic acid group) may be so protonated to form a salt and all such forms are included within the scope of this invention unless otherwise indicated.SELECTED DRAWING: None

Inventors:
ZHANG WEIJIANG
RONNIE CHEUNG
DIMITAR FILIPOV
JACK GREEN
LEE JUNNING
Application Number:
JP2018153560A
Publication Date:
November 15, 2018
Filing Date:
August 17, 2018
Export Citation:
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Assignee:
THERAVANCE BIOPHARMA ANTIBIOTICS IP LLC
International Classes:
C07K7/56; A61K9/19; A61K38/08; A61K47/18; A61K47/26; A61P31/04
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto