Title:
ヒドロゲルのバイオセンサとバイオセンサに基づいた健康のアラームシステム(HYDROGELBIOSENSORANDBIOSENSOR-BASEDHEALTHALARMSYSTEM)
Document Type and Number:
Japanese Patent JP2004507283
Kind Code:
A
Abstract:
A biosensor (10) has a hydrogel (30) in a rigid and preferably biocompatible enclosure (20). The hydrogel (30) includes an immobilized analyte binding molecule (ABM) and an immobilized analyte. The immobilized analyte competitively binds with free analyte to the ABM, thus changing the number of crosslinks in the hydrogel (30), which changes hydrogel swelling tendency (and thus the osmotic pressure) in its confined space in proportion to the concentration of free analyte concentration. By measuring the change in hydrogel pressure with a pressure transducer (40), the biosensor (10) is able to accurately measure the concentration of the free analyte molecule without the problem of oxygen limitations and interference encountered by prior art biosensors. A battery (64) powered telemeter (60) operably engaged to the pressure transducer (40) sends a radio data signal to a receiver (66) containing an alarm system operably attached to a computer (62). Furthermore, an alarm system utilizes such a sensor to automatically notify a person that the analyte level is outside desired predetermined parameters, and/or to automatically inject an agent to counteract the adverse analyte levels.
Inventors:
Han In Shuk
Magda Jules John
Ryu soak
Jean Young Sun
Magda Jules John
Ryu soak
Jean Young Sun
Application Number:
JP2001578926A
Publication Date:
March 11, 2004
Filing Date:
April 20, 2001
Export Citation:
Assignee:
M-Biotech Inc.
International Classes:
G01N33/483; A61B5/00; A61B5/145; G01N13/04; G01N33/487; G01N33/53; G01N33/543; G01N33/66; G01N1/02; (IPC1-7): A61B5/145; A61B5/00; G01N33/483; G01N33/66
Attorney, Agent or Firm:
Yu Saito
Fumihiko Ito
Fumihiko Ito