Title:
HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE
Document Type and Number:
Japanese Patent JP2020011968
Kind Code:
A
Abstract:
To provide methods for treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.SOLUTION: The present invention provides compounds having a structure of the formula I, and methods of making and using the same, including use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.SELECTED DRAWING: None
Inventors:
SARAH E DOWDELL
HILARY SCHENCK EIDAM
MARK ELBAN
RYAN MICHAEL FOX
MARLYS HAMMOND
MARK A HILFIKER
TRAM H HOANG
LARA S KALLANDER
BRIAN GRIFFIN LAWHORN
SHARADA MANNS
JOANNE PHILP
DAVID G WASHBURN
YE GUOSEN
HILARY SCHENCK EIDAM
MARK ELBAN
RYAN MICHAEL FOX
MARLYS HAMMOND
MARK A HILFIKER
TRAM H HOANG
LARA S KALLANDER
BRIAN GRIFFIN LAWHORN
SHARADA MANNS
JOANNE PHILP
DAVID G WASHBURN
YE GUOSEN
Application Number:
JP2019160658A
Publication Date:
January 23, 2020
Filing Date:
September 03, 2019
Export Citation:
Assignee:
GLAXOSMITHKLINE IP NO 2 LTD
International Classes:
C07D307/24; A61K31/341; A61K31/416; A61K31/443; A61K45/00; A61P1/16; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P11/00; A61P13/12; A61P17/00; A61P17/02; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P27/02; A61P27/06; A61P29/00; A61P35/00; A61P43/00; C07D307/68; C07D405/04; C07F9/655
Attorney, Agent or Firm:
Hiroyuki Nagai
Yukitaka Nakamura
Satoru Asakura
Hiroyuki Fujii
Hiroshi Sorimachi
Yukitaka Nakamura
Satoru Asakura
Hiroyuki Fujii
Hiroshi Sorimachi