Title:
【発明の名称】(8β)-1-アルキル-6-(置換)エルゴリンのシクロアルキルアミド類
Document Type and Number:
Japanese Patent JP2653835
Kind Code:
B2
Abstract:
This invention provides (8 beta )-N-cycloalkyl-1-alkyl-6-(substituted)ergoline-8-carboxamides of the formula wherein: R<1> is C1-C4 alkyl; R<2> is allyl or C1-C4 straight chain alkyl; R<3> is hydrogen or C1-C4 straight chain alkyl; R<4> is hydrogen, C1-C4 alkyl, hydroxy or C1-C4 alkoxy; m is 0, 1, 2 or 3; or a pharmaceutically acceptable acid addition salt thereof. The compounds are useful for blocking 5HT2 receptors in mammals having an excess of serotonin centrally or peripherally.
Inventors:
MAAKU MOOTENSEN FUOAMAN
UIRIAMU RII GAABURETSUTO
GIFUOODO PAANERU MAAZONI
KYASARIIN ROOZU HOITSUTEN
UIRIAMU RII GAABURETSUTO
GIFUOODO PAANERU MAAZONI
KYASARIIN ROOZU HOITSUTEN
Application Number:
JP14668988A
Publication Date:
September 17, 1997
Filing Date:
June 14, 1988
Export Citation:
Assignee:
IIRAI RIRII ANDO CO
International Classes:
A61P1/14; A61P3/04; A61P7/02; A61P9/08; A61K31/48; A61P9/10; A61P9/12; A61P25/04; A61P25/06; A61P25/18; A61P25/20; A61P25/24; A61P25/26; A61P43/00; C07D457/04; C07D457/06; (IPC1-7): C07D457/04; A61K31/48; C07D457/06
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)