Title:
【発明の名称】プロスタグランジンアンタゴニストとして有用な10-アシル-ジベンゾ(B,F)(1,4)-オキサゼピンおよびそれらのチアゼピン類縁体
Document Type and Number:
Japanese Patent JPH07501054
Kind Code:
A
Abstract:
PCT No. PCT/US92/08103 Sec. 371 Date Mar. 3, 1994 Sec. 102(e) Date Mar. 3, 1994 PCT Filed Sep. 28, 1992 PCT Pub. No. WO93/09104 PCT Pub. Date May 13, 1993.The present invention provides substituted dibenzoxazepine compounds of Formula I: which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
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Inventors:
Timothy Joseph, Hagen
Chandra Kumar, Nizar Samuel
Harinan, E. Ann
Lao Shashida N.
Pizzere, Burnett Sylvain
Chandra Kumar, Nizar Samuel
Harinan, E. Ann
Lao Shashida N.
Pizzere, Burnett Sylvain
Application Number:
JP50839793A
Publication Date:
February 02, 1995
Filing Date:
September 28, 1992
Export Citation:
Assignee:
G.D.Searle & Company
International Classes:
A61K31/554; A61P1/00; A61P3/02; A61P9/06; A61K31/55; A61P11/00; A61P13/02; A61P15/00; A61P25/04; A61P25/08; A61P43/00; C07D267/20; C07D281/16; C07D413/12; (IPC1-7): C07D267/20; A61K31/55; C07D281/16; C07D413/12
Attorney, Agent or Firm:
Akira Asamura (3 outside)