Title:
【発明の名称】側鎖フルオロケトンを有する4-アザステロイド
Document Type and Number:
Japanese Patent JPH09503227
Kind Code:
A
Abstract:
PCT No. PCT/EP95/02649 Sec. 371 Date May 31, 1996 Sec. 102(e) Date May 31, 1996 PCT Filed Jul. 7, 1995 PCT Pub. No. WO96/03422 PCT Pub. Date Feb. 8, 1996The present invention provides compounds of formula (D wherein the symbol +E,uns - - -+EE represents a single or a double bond; R is a hydrogen atom or a C1-C4 alkyl group; A is a single bond or a straight or branched C1-C6 alkylene chain; B is a straight or branched C1-C12 alkylene group optionally substituted by one or more aryl groups or fluorine atoms; W is a group R1 or (a) wherein R1 is a straight or branched C-C6 alkyl group unsubstituted or substituted by one or more fluorine atoms, provided that at least a fluorine atom is present in B or W. The compounds of the invention are useful as testosterone 5 alpha -reductase inhibitors.
Inventors:
Pants collar, Achille
Neshi, Maruella
Day Sale, Enrico
Neshi, Maruella
Day Sale, Enrico
Application Number:
JP50539395A
Publication Date:
March 31, 1997
Filing Date:
July 07, 1995
Export Citation:
Assignee:
Falmatia Esset Pear
International Classes:
A61P3/00; C07J3/00; A61K31/59; C07J73/00; (IPC1-7): C07J3/00; A61K31/59
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)