Title:
【発明の名称】アシル補酵素A:コレステロールアシルトランスフェラーゼ(ACAT)の阻害剤としての新規なN-アリールおよびN-ヘテロアリール尿素誘導体
Document Type and Number:
Japanese Patent JPH07503737
Kind Code:
A
Abstract:
PCT No. PCT/US93/03539 Sec. 371 Date Jan. 17, 1995 Sec. 102(e) Date Jan. 17, 1995 PCT Filed Apr. 20, 1993 PCT Pub. No. WO93/24458 PCT Pub. Date Dec. 9, 1993A compound of the formula and the pharmaceutically acceptable salts thereof, wherein R17, R18 and R1 are as defined below. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.
Inventors:
Hamanaka, Ernest S
Application Number:
JP50052294A
Publication Date:
April 20, 1995
Filing Date:
April 20, 1993
Export Citation:
Assignee:
Father Incorporated
International Classes:
A61K31/00; A61K31/38; A61K31/381; A61K31/44; A61K31/4418; A61K31/4433; A61K31/47; A61P3/06; A61P9/10; C07C275/00; C07C275/28; C07D239/42; C07C335/06; C07C335/14; C07D213/60; C07D213/75; C07D215/38; C07D239/58; C07D333/58; C07D333/66; C07D409/12; (IPC1-7): C07C275/28; C07D409/12; C07D333/58; C07D239/42; C07D215/38; C07D213/60; C07C335/14; C07C335/06; A61K31/47; A61K31/44; A61K31/38
Domestic Patent References:
| JPH03261755A | 1991-11-21 | |||
| JPH02258756A | 1990-10-19 | |||
| JP91013871Y | ||||
| JPH0592950A | 1993-04-16 |
Foreign References:
| US3426031A | 1969-02-04 |
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)