Title:
【発明の名称】アミノメチル アリール化合物;ドーパミンレセプター亜型選択性リガンド
Document Type and Number:
Japanese Patent JP2918002
Kind Code:
B2
Abstract:
Disclosed are compounds of formula (I), where S and V are various organic or inorganic substituents; G and K are the same or different and represent N or CR' where R' is an organic or inorganic substituent; R is hydrogen or an alkyl group; R1, X, Y, Z and T are organic or inorganic substituents; and R2 and R3 represent hydrogen or organic substituents; or NR2R3 together represents a heterocyclic ring system; and the pharmaceutically acceptable salts thereof; which are highly selective partial agonists or antagonists at brain dopamine receptor subtypes and, thus, are useful in the diagnosis and treatment of affective disorders such as schizophrenia and depression as well as certain movement disorders such as Parkinsonism.
Inventors:
YUAN JUN
SAAKAUFU ANDORYUU
SAAKAUFU ANDORYUU
Application Number:
JP51712096A
Publication Date:
July 12, 1999
Filing Date:
November 22, 1995
Export Citation:
Assignee:
NYUUROGEN CORP
International Classes:
C07D239/26; A61K31/135; A61K31/4412; A61K31/4418; A61K31/4427; A61K31/445; A61K31/451; A61K31/505; A61P25/00; A61P25/18; A61P25/24; A61P25/26; A61P43/00; C07C211/27; C07C211/29; C07C215/50; C07C217/58; C07C255/49; C07C317/32; C07C317/48; C07D211/14; C07D211/70; C07D211/82; C07D213/38; C07D239/42; C07D295/096; C07D401/06; (IPC1-7): C07C211/27; A61K31/445; A61K31/505; C07D213/38; C07D239/26; C07D239/42; C07D401/06
Domestic Patent References:
| JP62226977A |
Other References:
【文献】Chemical Abstracts(1978)89[13]P.121 no.100486u
【文献】Chemical Abstracts(1987)106[25]P.597 no.119384a
【文献】Chemical Abstracts(1987)106[25]P.597 no.119384a
Attorney, Agent or Firm:
Hidekazu Miyoshi (1 outside)