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Title:
【発明の名称】新規中間体を経由するベンゾオキサジノン類の不斉合成
Document Type and Number:
Japanese Patent JP2001519810
Kind Code:
A
Abstract:
The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one of formula (VI-i) which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.

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Inventors:
Earrings, Michael, Yi.
Chen, Chen, Wai.
Chaudhry, Anusya.
Ladesca, Lillian, A.
Tan, rush.
Csao, Darian.
Application Number:
JP54288698A
Publication Date:
October 23, 2001
Filing Date:
April 02, 1998
Export Citation:
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Assignee:
DuPont Pharmaceuticals Company
Merck & Company, Inc.
International Classes:
A61P31/18; A61P37/04; C07C213/00; C07C213/02; C07C215/70; C07D265/16; C07C221/00; C07C225/22; C07D265/18; C07C215/68; C07C217/58; (IPC1-7): C07D265/16; A61P31/18; A61P37/04; C07C213/02; C07C215/70; C07C221/00; C07C225/22
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)



 
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