Title:
【発明の名称】プロテインチロシンキナーゼ阻害剤としての二環式ヘテロ芳香族化合物
Document Type and Number:
Japanese Patent JP2000514445
Kind Code:
A
Abstract:
Protein tyrosine kinase inhibitor compounds are described, as are methods for their preparation, pharmaceutical compositions including such compounds, and their use in medicine, for example in the treatment of cancer and psoriasis. In particular, the use of an inhibitor of both EGFR and erbB-2 in the treatment of a susceptible malignancy, such as cancer or a malignant tumour, is described.
Inventors:
George, Stuart, Cockerill
Malcolm, Cleve, Carter
Stephen, Barry, Gun Trip
Kathryn, Jane, Smith
Malcolm, Cleve, Carter
Stephen, Barry, Gun Trip
Kathryn, Jane, Smith
Application Number:
JP50559898A
Publication Date:
October 31, 2000
Filing Date:
July 11, 1997
Export Citation:
Assignee:
GLAXO GROUP LTD.
International Classes:
A61K31/519; A61K31/5355; A61P17/16; A61P35/00; A61P43/00; C07D209/08; C07D215/00; C07D231/56; C07D235/08; C07D401/06; C07D407/12; C07D471/04; C07D493/08; C07D519/00; A61K; C07D; (IPC1-7): C07D471/04; A61K31/519; A61K31/5355; A61P17/16; A61P35/00; A61P43/00; C07D231/56
Attorney, Agent or Firm:
Kazuo Sato (2 outside)