Title:
【発明の名称】薬剤の徐放性マトリックスとしての、官能基を有する架橋高アミロースデンプン
Document Type and Number:
Japanese Patent JP2002504508
Kind Code:
A
Abstract:
The present invention is concerned with a solid slow release oral pharmaceutical dosage unit resistant to amylase which comprises a solid dosage unit made up of an admixture of a therapeutic dosage of an orally effective pharmaceutical product, an optional polysaccharide or polyol, and cross-linked high amylose starch, wherein the cross-linking of the high amylose starch has been carried out with a covalent or non-covalent cross-linking agent with from about 0.1 g to about 30 g of cross-linking agent per 100 g of high amylose starch.
Inventors:
Renarts, Vincent
Francois, Tuinard
Matthew, Mearsy, A.
Ispas-Suzabo, Pompira
Francois, Tuinard
Matthew, Mearsy, A.
Ispas-Suzabo, Pompira
Application Number:
JP2000533104A
Publication Date:
February 12, 2002
Filing Date:
February 24, 1999
Export Citation:
Assignee:
Renarts, Vincent
Francois, Tuinard
Matthew, Mearsy, A.
Ispas-Suzabo, Pompira
Francois, Tuinard
Matthew, Mearsy, A.
Ispas-Suzabo, Pompira
International Classes:
A61K9/20; A61K9/22; A61K9/26; A61K31/137; A61K31/167; A61K31/192; A61K47/10; A61K47/34; A61K47/36; C08B33/00; C08B35/00; (IPC1-7): A61K9/20; A61K31/137; A61K31/167; A61K31/192; A61K47/10; A61K47/34; A61K47/36; C08B33/00; C08B35/00
Domestic Patent References:
| JPH08507769A | 1996-08-20 | |||
| JPH0912601A | 1997-01-14 | |||
| JPS5818322A | 1983-02-02 | |||
| JPH10500712A | 1998-01-20 | |||
| JPH06271704A | 1994-09-27 | |||
| JPH11515063A | 1999-12-21 | |||
| JPS63246352A | 1988-10-13 |
Foreign References:
| US5456921A | 1995-10-10 | |||
| WO1997016595A1 | 1997-05-09 |
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)