Title:
【発明の名称】((シクロ)アルキル置換)-γ-アミノ酪酸誘導体(=GABA類似体)、それらの製造および神経学的疾患の治療における使用
Document Type and Number:
Japanese Patent JP2002508361
Kind Code:
A
Abstract:
Novel amines of formulas (1A) and (1B) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, inflammatory diseases, and gastrointestinal disorders, especially IBS. Processes for the preparation and intermediates useful in the preparation are also disclosed. R is sulfonamide, amide, sulfonic acid, or phosphonic acid.
Inventors:
Thomas Richard Belliotti
Justin Stephen Bryans
Thomas Capilis
David Christopher Howell
Claire Octevier Nene
David Juergen Wustrow
Justin Stephen Bryans
Thomas Capilis
David Christopher Howell
Claire Octevier Nene
David Juergen Wustrow
Application Number:
JP2000539001A
Publication Date:
March 19, 2002
Filing Date:
November 10, 1998
Export Citation:
Assignee:
Warner-Lambert Company
International Classes:
A61K31/35; A61K31/351; A61K31/38; A61K31/382; A61K31/41; A61K31/4245; A61K31/433; A61K31/4427; A61K31/443; A61K31/4433; A61K31/445; A61K31/4465; A61K31/454; A61K31/66; A61K31/665; C07D285/08; A61P1/00; A61P9/10; A61P25/00; A61P25/04; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P29/00; A61P43/00; C07C233/36; C07C239/14; C07C259/06; C07C309/25; C07C311/05; C07C311/09; C07C311/32; C07C311/33; C07D211/26; C07D211/28; C07D211/54; C07D257/04; C07D271/06; C07D271/07; C07D285/18; C07D291/04; C07D309/04; C07D335/02; C07D401/06; C07D405/06; C07D407/06; C07D409/06; C07D413/06; C07D417/06; C07D419/06; C07F9/38; C07F9/59; C07F9/655; C07F9/6553; A61K; C07C; C07D; (IPC1-7): C07D257/04; A61K31/41; A61K31/4245; A61K31/433; A61K31/66; A61P1/00; A61P25/00; A61P25/08; A61P25/22; A61P25/24; A61P25/28; A61P29/00; A61P43/00; C07D271/06; C07D285/08; C07D291/04
Attorney, Agent or Firm:
Chika Takagi (1 person outside)