Title:
【発明の名称】NPY拮抗薬としてのジヒドロピラジン誘導体
Document Type and Number:
Japanese Patent JP2003502374
Kind Code:
A
Abstract:
The present invention provides a series of non-peptidergic antagonists of NPY comprising piperidine and piperazine derivatives of 4-phenyl-1,4-dihydropyrazines of the Formula Iwherein R, R1 X, Y and Z are defined herein. As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
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Inventors:
Sit, Sing-Yuan
Huang, Jatsuhon
Huang, Jatsuhon
Application Number:
JP2001504382A
Publication Date:
January 21, 2003
Filing Date:
June 06, 2000
Export Citation:
Assignee:
Bristol-Myers Squibb Company
International Classes:
A61K31/496; A61K31/497; A61P1/00; A61P1/04; A61P1/14; A61P3/04; A61P3/10; A61P5/00; A61P5/06; A61P5/48; A61P7/02; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P11/06; A61P11/08; A61P13/02; A61P13/12; A61P15/10; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/18; A61P25/20; A61P25/26; A61P25/28; A61P29/00; A61P43/00; C07D241/06; C07D401/12; (IPC1-7): C07D241/06; A61K31/496; A61K31/497; A61P1/00; A61P1/04; A61P1/14; A61P3/04; A61P3/10; A61P5/00; A61P5/06; A61P5/48; A61P7/02; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P11/06; A61P11/08; A61P13/02; A61P13/12; A61P15/10; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/18; A61P25/20; A61P25/26; A61P25/28; A61P29/00; A61P43/00; C07D401/12
Attorney, Agent or Firm:
Takehiko Saito (1 outside)