Title:
【発明の名称】ドーパミン及びセロトニン輸送体リガンド並びにイメージング剤
Document Type and Number:
Japanese Patent JPH11514368
Kind Code:
A
Abstract:
This invention presents a series of novel tropane-based derivatives complexed with either technetium or rhenium that are specific for central nervous system receptors, in particular, dopamine or serotonin receptors. The compounds of the invention have utility, inter alia, as imaging agents for CNS receptors. Methods of using these novel compounds as imaging agents are presented, as are intermediates and methods for making these novel compounds
Inventors:
Khun, Hank F
Migala, Sanas
Khun, May-Pin
Curls
Migala, Sanas
Khun, May-Pin
Curls
Application Number:
JP51609197A
Publication Date:
December 07, 1999
Filing Date:
October 21, 1996
Export Citation:
Assignee:
UNIV PENNSYLVANIA (US)
International Classes:
A61K49/00; A61K51/00; A61K51/04; A61M36/14; A61N5/10; C07D451/02; C07F13/00; (IPC1-7): C07D451/02; A61K49/00; A61N5/10; C07F13/00
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)