Title:
【発明の名称】ターミナル補体成分を使用する薬物送達
Document Type and Number:
Japanese Patent JP2000510461
Kind Code:
A
Abstract:
Methods for treatment of a subject with therapeutic or diagnostic agents by delivery of the therapeutic or diagnostic agents to the subject via sublytic amounts of terminal complement membrane attack acomplex (MAC) transmembrane channels are described. Also described are methods for delivery of therapeutic or diagnostic agents to cells in vitro via sublytic amounts of MAC transmembrane channels. Pharmaceutical preparations containing MAC transmembrane channel forming agents and kits for the formation of sublytic amounts of MAC transmembrane channels also are provided.
Inventors:
Halperin, Jose A.
Goldstein, Daniel Jay.
Acosta, Fan A.
Goldstein, Daniel Jay.
Acosta, Fan A.
Application Number:
JP53920597A
Publication Date:
August 15, 2000
Filing Date:
April 30, 1997
Export Citation:
Assignee:
President and Fellows of Harvard College
International Classes:
A61K38/00; A61K31/00; A61K38/04; A61K38/17; A61K45/00; A61K47/42; A61K48/00; A61K51/12; A61P31/00; A61P31/12; A61P33/00; A61P35/00; A61P43/00; C07K16/00; C12N15/87; G01N33/536; G01N33/569; G01N33/573; G01N33/68; (IPC1-7): A61K38/00; A61P31/12; A61P31/00; A61P33/00; A61P35/00; A61P43/00; A61K45/00; A61K48/00
Attorney, Agent or Firm:
Kiyokazu Kazuwa (1 person outside)