【発明の名称】エンドセリン転換酵素阻害剤

Title:

【発明の名称】エンドセリン転換酵素阻害剤

Document Type and Number:

Japanese Patent JPH06505474

Kind Code:

A

Abstract:

Compounds are disclosed which inhibit endothelin converting enzyme. These compounds are useful for treating hypertension, congestive heart failure, myocardial infarction, reperfusion injury, coronary angina, cerebral vasospasm, acute renal failure, non-steroidal antiinflammatory drug induced gastric ulceration, cyclosporin induced nephrotoxicity, endotoxin-induced toxicity, asthma and atherosclerosis.

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Inventors:

Shiosaki, Kazumi
Tasker, Andrew S
Opgenose, Terry J.A.

Application Number:

JP50518292A

Publication Date:

June 23, 1994

Filing Date:

November 08, 1991

Export Citation:

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Assignee:

Abbot Laboratories

International Classes:

C08G59/68; A61K38/55; A61P1/00; A61P9/00; A61P9/08; A61P9/10; A61P9/12; A61P11/00; A61P13/02; A61P15/00; C07K5/02; C07K5/06; C07K5/065; C07K5/08; C07K5/083; C07K5/093; C07K7/02; C08G59/70; C08J5/24; C09J163/00; H01L23/29; H01L23/31; A61K38/00; (IPC1-7): C07K5/06; A61K37/64; C07K5/08

Attorney, Agent or Firm:

Yoshio Kawaguchi (2 outside)

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