【発明の名称】フルプロステノールおよび関連プロスタグランジンF2α類似体の内部1,15-ラクトン、ならびに緑内障および眼高血圧の治療におけるそれらの使用

Title:

Document Type and Number:

Japanese Patent JP2003531824

Kind Code:

A

Abstract:

Novel derivatives of prostaglandin compounds of the F-series (PGF), specifically macrocyclic internal 1,15-lactones of fluprostenol and related PGF analogs, such as cloprostenol or latanoprost. The novel analogs can be formulated into ophthalmic solutions and topically applied for the treatment of the increased intraocular pressure caused by glaucoma and the reduction of ocular hypertension.

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Inventors:

Maxey, Kirk, M.
Stanton, Michelle, Elle.

Application Number:

JP2001556865A

Publication Date:

October 28, 2003

Filing Date:

February 01, 2001

Export Citation:

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Assignee:

Cayman Chemical Campany, Inc.

International Classes:

A61K9/08; A61K31/365; A61P27/02; A61P27/06; A61P43/00; C07C405/00; C07D267/00; C07D313/00; C07D321/00; C07D327/02; (IPC1-7): C07D313/00; A61K9/08; A61K31/365; A61P27/02; A61P27/06; A61P43/00

Attorney, Agent or Firm:

Masao Okabe (10 outside)

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