Title:
【発明の名称】タンパク質の放射線標識に関する更なる改良
Document Type and Number:
Japanese Patent JPH07502502
Kind Code:
A
Abstract:
PCT No. PCT/GB92/02322 Sec. 371 Date Jun. 16, 1994 Sec. 102(e) Date Jun. 16, 1994 PCT Filed Dec. 15, 1992 PCT Pub. No. WO93/11796 PCT Pub. Date Jun. 24, 1993A structurally modified protein is provided that will bind to a tumor-associated structure wherein the amino group in at least one basic amino acid in the binding protein is structurally modified to convert the amino group, -NH2, to the grouping -NH-CO-X-NHR in which R is H or an amino protecting group and the grouping -CO-X-NHR is the residue of a peptide of the formula NHR-X-COOH capable of acting as a substrate for a phosphokinase.
Inventors:
Clayton, Andrew Malcolm
Application Number:
JP51073993A
Publication Date:
March 16, 1995
Filing Date:
December 15, 1992
Export Citation:
Assignee:
BTG International Limited
International Classes:
A61K47/48; A61K51/00; A61K51/08; C07K1/107; C07K1/113; C07K1/13; C07K7/06; C07K16/00; C07K17/02; G01N33/53; C07K19/00; G01N33/534; G01N33/574; (IPC1-7): C07K19/00; A61K47/48; A61K51/00; C07K1/13; C07K16/00; G01N33/53; G01N33/534
Attorney, Agent or Firm:
Kyozo Yuasa (6 people outside)