Title:
【発明の名称】非抗原性即素複合体およびインターナライジング受容体システムの融合タンパク
Document Type and Number:
Japanese Patent JP2001503253
Kind Code:
A
Abstract:
A conjugate of a toxin and a cytokine, and a fusion protein comprising a bispecific antibody that has a first specificity for a cell marker specific to a malignant cell and a second specificity for a region of IL-15alpha, each optionally further comprising a radionuclide, are useful therapeutic reagents for treating leukemias and lymphomas.
Inventors:
Goldenberg, David M
Application Number:
JP51840298A
Publication Date:
March 13, 2001
Filing Date:
October 14, 1997
Export Citation:
Assignee:
Immunomedics, Inc.
International Classes:
A61K38/00; A61K39/395; A61K47/48; A61K51/00; A61K51/08; A61P35/00; A61P35/02; C12N15/09; C07K14/54; C07K14/715; C07K16/28; C07K16/46; C07K19/00; (IPC1-7): C12N15/09; A61K38/00; A61K39/395; A61K51/00; C07K14/54; C07K16/46; C07K19/00
Attorney, Agent or Firm:
Nao Okuyama (3 others)