Title:
【発明の名称】HIVプロテアーゼ阻害剤インジナビル及び逆転写酵素阻害剤3TCを必要に応じてAZT、DDI、又はDDCと共に用いるHIV感染の組合せ治療
Document Type and Number:
Japanese Patent JPH10513186
Kind Code:
A
Abstract:
The combination of the HIV protease inhibitor Compound J, 3TC, and, optionally AZT, ddI, or ddC, is useful in the inhibition of HIV protease, the inhibition of HIV reverse transcriptase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Inventors:
Kodaik Widgets, Jee Free A
Emini, Emilio A
Emini, Emilio A
Application Number:
JP52373996A
Publication Date:
December 15, 1998
Filing Date:
January 29, 1996
Export Citation:
Assignee:
Merck End Company, Inc.
International Classes:
A61K31/18; A61K31/496; A61K31/495; A61K31/505; A61K31/513; A61K31/70; A61K31/7068; A61K31/7072; A61P31/12; A61P31/18; A61P43/00; C07D401/06; C07D411/04; C07H5/10; C07H19/00; C07H19/06; A61K; C07D; (IPC1-7): A61K31/495; A61K31/505; A61K31/70
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)