Title:
【発明の名称】ヒト及びマウスGタンパク質結合受容体EDG6(内皮分化遺伝子)及びその用途
Document Type and Number:
Japanese Patent JP2002525050
Kind Code:
A
Abstract:
The invention relates to the G protein-coupled EDG6 receptor, fragments, variants and mutations thereof, as well as to its use. Areas of application of the invention include molecular biology, pharmacy and medicine. The aim of the invention is to isolate and identify a further member of the family of EDG receptors and to permit its use for medical purposes. The new human EDG6 receptor comprises 384 amino acids of sequence 1 having seven transmembrane domains. The receptor has a possible N-terminal glycolysis site, three possible palmitoylation sites, between 12 and 15 amino acids in the C-terminal position of the seventh transmembrane domain and four possible C-terminal proteinkinase C-phosphorylation sites. The invention further relates to the use of the EDG6 receptor, its fragments, variants and mutations and possibly its binding partners for therapeutic methods and treatments.
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Inventors:
Grayler, Marx
Bernhard, Gunther
Lip, martin
Bernhard, Gunther
Lip, martin
Application Number:
JP2000570311A
Publication Date:
August 13, 2002
Filing Date:
September 10, 1999
Export Citation:
Assignee:
Max-Dell Brook-Centrum Fur Moreclere Medizin
International Classes:
A01K67/027; A61K38/00; A61K39/395; A61K48/00; A61P9/00; A61P29/00; A61P37/00; A61P43/00; C07K14/705; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12P21/08; C12Q1/68; G01N33/53; G01N33/566; G01N33/577; (IPC1-7): C12N15/09; A01K67/027; A61K38/00; A61K39/395; A61K48/00; A61P9/00; A61P29/00; A61P37/00; A61P43/00; C07K14/705; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/68; G01N33/53; G01N33/566; G01N33/577
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)