Title:
【発明の名称】宿主細胞における蛋白産生の改良
Document Type and Number:
Japanese Patent JPH10507625
Kind Code:
A
Abstract:
PCT No. PCT/AU95/00553 Sec. 371 Date Feb. 25, 1997 Sec. 102(e) Date Feb. 25, 1997 PCT Filed Aug. 30, 1995 PCT Pub. No. WO96/06937 PCT Pub. Date Mar. 7, 1996Method of increasing protein production in a host cell where the nucleic acid encoding the protein has an A and/or T rich region in an exon. The method comprising lowering the amount of A and/or T rich region and transfecting a host cell with the altered nucleic acid and obtaining expression of the nucleic acid. The invention also relates to the recombinant nucleic acid constructs, purified protein preparations and pharmaceutical compositions produced as well as methods of treatment utilizing the purified protein preparation.
Inventors:
Millland, Julie
Loveland, Bruce
Christiansen, Dale
Mackenzie, Ian F. C.
Loveland, Bruce
Christiansen, Dale
Mackenzie, Ian F. C.
Application Number:
JP50835696A
Publication Date:
July 28, 1998
Filing Date:
August 30, 1995
Export Citation:
Assignee:
The Austin Research Institute
International Classes:
A61K35/12; A61K38/00; A61K48/00; A61P13/02; A61P15/00; A61P29/00; A61P31/12; A61P35/00; A61P43/00; C07K14/705; A01K67/027; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12R1/91; (IPC1-7): C12N15/09; A01K67/027; A61K35/12; A61K38/00; A61K48/00; C07K14/705; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Kiyoya Fujino
Previous Patent: 遺伝子発現、遺伝子産物機能および工学処理された宿主細胞の調節可能な...
Next Patent: 細胞サイクルによって変化する細胞に特異的な活性化合物を用いる血管系...
Next Patent: 細胞サイクルによって変化する細胞に特異的な活性化合物を用いる血管系...