Title:
【発明の名称】ファルネシル蛋白質トランスフェラーゼの阻害剤
Document Type and Number:
Japanese Patent JPH0733348
Kind Code:
B2
Abstract:
This invention relates to pharmaceutical compounds of structural formula (I): and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.
Inventors:
Xio Bax Sing
The erald f bills
Russell B. Ringham
Keith C. Silverman
Deborah El Zink
The erald f bills
Russell B. Ringham
Keith C. Silverman
Deborah El Zink
Application Number:
JP32781292A
Publication Date:
April 12, 1995
Filing Date:
December 08, 1992
Export Citation:
Assignee:
Merck End-Campany Inc.
International Classes:
A61K31/19; A61K31/23; A61P35/00; A61P43/00; C07C55/02; C07C57/13; C07C57/34; C07C69/593; C07C69/602; C12N1/14; C12N9/99; C12P7/44; C12P7/64; C12P17/04; C12R1/645; (IPC1-7): C07C55/02; A61K31/19; A61K31/23; C07C57/34; C07C69/593; C12N1/14; C12P7/44; C12P17/04
Other References:
ＰＨＹＴＯＣＨＥＭＩＳＴＲＹ，１９７７，Ｖｏｌ．１６，１３４−１３５
ＰＨＹＴＯＣＨＥＭＩＳＴＲＹ，１９８２，Ｖｏｌ．２１，Ｎｏ．７，１７８６−１７８８
ＰＨＹＴＯＣＨＥＭＩＳＴＲＹ，１９８２，Ｖｏｌ．２１，Ｎｏ．７，１７８６−１７８８
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)
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