Title:
【発明の名称】インターロイキン―1インヒビター
Document Type and Number:
Japanese Patent JP3192651
Kind Code:
B2
Abstract:
A substantially purified interleukin-1 inhibitor (IL-li) which is active against interleukin-1 alpha or interleukin-1 beta or both of these substances. A recombinant-DNA method for the production of an interleukin-1 inhibitor (IL-li), and an isolated DNA sequence encoding a physiologically functional interleukin-1 inhibitor (IL-li).
Inventors:
Hannon, Charles, Etch.
Eisenberg, Stefan, Pee.
Thompson, Robert, Sea.
Allend, William, Pea.
Joslyn, Fennec, Gee.
Somer, Andreas
Eisenberg, Stefan, Pee.
Thompson, Robert, Sea.
Allend, William, Pea.
Joslyn, Fennec, Gee.
Somer, Andreas
Application Number:
JP50639389A
Publication Date:
July 30, 2001
Filing Date:
May 25, 1989
Export Citation:
Assignee:
Amgen, Incorporated
The University of Colorado Foundation
The University of Colorado Foundation
International Classes:
C12N15/09; A61K38/00; A61P19/02; A61P29/00; A61P37/06; C07K14/00; C07K14/47; C07K14/54; C07K16/18; C12N1/21; C12N5/10; C12N15/12; C12N15/24; C12N15/25; C12N15/70; C12P21/00; C12P21/02; C12P21/08; C12R1/19; C12R1/91; (IPC1-7): C07K14/47; A61K38/00; A61P37/00; C12N1/21; C12N5/10; C12N15/00; C12P21/02
Domestic Patent References:
| JP2500643A |
Other References:
Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ，２０，（１９９０），６８３−６８９
Ｊ．Ｅｘｐ．Ｍｅｄ．，１６３，（１９８６），５１１−５１９
Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ，１３４（６），（１９８５），３８８２−３８８６
Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ，１３９（５），（１９８７），１５４１−１５４５
Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ，１３９（５），（１９８７），１５４６−１５４９
Ｊ．Ｅｘｐ．Ｍｅｄ．，１６３，（１９８６），５１１−５１９
Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ，１３４（６），（１９８５），３８８２−３８８６
Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ，１３９（５），（１９８７），１５４１−１５４５
Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ，１３９（５），（１９８７），１５４６−１５４９
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)