Title:
【発明の名称】第一遷移系列元素に対してキレート化親和性および選択性のある化合物とその使用
Document Type and Number:
Japanese Patent JP2003523394
Kind Code:
A
Abstract:
This invention involves the use of a class of compounds with chelation affinity and selectivity for first transition series elements. Application or administration of the free or conjugated compound, or physiological salts of the free or conjugated compound, results in decrease of the bioavailability and/or chemical action of first transition series elements. These characteristics make such compounds useful in cosmetics and personal care products to decrease odor arising from microbial growth on body surfaces and in body cavities, decrease microbial growth on teeth, plaque, and gums that cause tooth decay and gum disease, inhibition of oxidative damage to the skin, inhibition of enzymatic action of metalloenzymes dependent on first transition series elements, and inhibition of reperfusion injury.
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Inventors:
Winchel, Harry S.
Klein, Joseph Wai.
Simon, Elliott Dee.
Sijon, Rosa El.
Klein, Ofer
The Clad, Heim
Klein, Joseph Wai.
Simon, Elliott Dee.
Sijon, Rosa El.
Klein, Ofer
The Clad, Heim
Application Number:
JP2001561327A
Publication Date:
August 05, 2003
Filing Date:
February 14, 2001
Export Citation:
Assignee:
Concat limited
International Classes:
C07D257/02; A61K6/00; A61K8/00; A61K8/41; A61K8/49; A61K31/132; A61K31/133; A61K31/33; A61K31/395; A61K31/675; A61P1/02; A61P9/00; A61P17/00; A61P39/06; A61P43/00; A61Q11/00; A61Q15/00; (IPC1-7): A61K31/675; A61K7/16; A61K7/32; A61K31/132; A61K31/133; A61K31/395; A61P1/02; A61P9/00; A61P17/00; A61P39/06; A61P43/00; C07D257/02
Attorney, Agent or Firm:
Takashi Ishida (4 others)