Title:
【発明の名称】ICE/ced-3ファミリーのシステインプロテアーゼのインヒビター
Document Type and Number:
Japanese Patent JP2003519680
Kind Code:
A
Abstract:
This invention s directed to novel oxamyl dipeptide ICE/ced-3 family inhibitor compounds having the following structure:wherein A, B, R, R1, p and q are as defined herein. The invention s all directed to pharmaceutical compositions containing one or more of thee compound, as well as to the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that to undergo a transplantation procedure.
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Inventors:
Turnanski, Robert Jay.
Gladstone, Patricia El.
Tomaselli, Kevin Jay.
Gladstone, Patricia El.
Tomaselli, Kevin Jay.
Application Number:
JP2001551844A
Publication Date:
June 24, 2003
Filing Date:
January 10, 2001
Export Citation:
Assignee:
Aiden Pharmaceuticals, Inc.
International Classes:
C12N9/99; A61K31/18; A61K31/404; A61K31/445; A61K31/662; A61K38/55; A61P7/00; A61P7/06; A61P9/10; A61P11/00; A61P19/08; A61P25/00; A61P29/00; A61P31/00; A61P35/00; A61P37/00; A61P37/02; A61P41/00; A61P43/00; C07C311/51; C07D209/42; C07D211/60; C07K5/06; C07K5/065; C12N5/07; C12N5/071; A61K38/00; (IPC1-7): C07C311/51; A61K31/18; A61K31/404; A61K31/445; A61K31/662; A61K38/55; A61P7/00; A61P7/06; A61P9/10; A61P11/00; A61P19/08; A61P25/00; A61P29/00; A61P31/00; A61P37/02; A61P43/00; C07D209/42; C07D211/60; C07K5/06; C12N9/99
Attorney, Agent or Firm:
Shusaku Yamamoto (2 outside)