Title:
【発明の名称】免疫化同種異系骨髄ドナーからの活性腫瘍特異的免疫化の移入のための方法および組成物
Document Type and Number:
Japanese Patent JPH09509649
Kind Code:
A
Abstract:
This invention provides a method of improving a transplantation of hematopoietic cells from a donor to a recipient to treat a hematopoietic cell tumor in the recipient comprising immunizing the donor's hematopoietic cells with an antigen specific for the recipient's hematopoietic cell tumor, and transplanting the donor's immunized hematopoietic cells to the recipient. Also provided is a composition comprising purified hematopoietic cells primed to produce an immunological response to foreign tumor specific antigen. Also provided is a method of treating a tumor by the transplantation of hematopoietic cells from a donor to a recipient to treat the tumor in the recipient comprising immunizing the donor's hematopoietic cells with an antigen specific for the recipient's tumor, and transplanting the donor's immunized hematopoietic cells to the recipient.
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Inventors:
Kirk, Rally W.
Longo, Dan El.
Longo, Dan El.
Application Number:
JP51458495A
Publication Date:
September 30, 1997
Filing Date:
November 16, 1994
Export Citation:
Assignee:
US HEALTH (US)
International Classes:
C12N5/07; A61K35/28; A61K39/00; A61K39/395; A61P35/00; C12N5/077; C12N5/0781; C12N5/09; A61K35/12; (IPC1-7): A61K35/28; A61K39/00; A61K39/395; C12N5/06
Attorney, Agent or Firm:
Shusaku Yamamoto