Title:
【発明の名称】オリゴヌクレオチド合成の方法および手段
Document Type and Number:
Japanese Patent JP3161730
Kind Code:
B2
Abstract:
PCT No. PCT/SE91/00797 Sec. 371 Date Jul. 24, 1992 Sec. 102(e) Date Jul. 24, 1992 PCT Filed Nov. 25, 1991 PCT Pub. No. WO92/09615 PCT Pub. Date Jun. 11, 1992Support system for the synthesis of oligonucleotides wherein the first nucleoside is bound to the support via a silylether linkage, especially of the formula wherein B is a nucleoside or deoxynucleoside base. R1 is a protecting group. R2 is -H, -OH, or -OR5, in which R5 is a protecting group. R3, R4 and X each represent alkyl, aryl, cycloalkyl, alkenyl, aralkyl, cycloalkylalkyl, alkyloxy, aryloxy, cycloalkyloxy, alkenyloxy, aralkyloxy. S is a solid support, whereby not more than one of R3, R4 and X represent alkyloxy, aryloxy, cycloalkyloxy, alkenyloxy, aralkyloxy or cycloalkylalkyloxy.
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Inventors:
Holmberg, Lars
Application Number:
JP50010592A
Publication Date:
April 25, 2001
Filing Date:
November 25, 1991
Export Citation:
Assignee:
Amersham, Pharmacia, Biotech, Actiebo Lagu
International Classes:
C07H19/04; C07H19/06; C07H21/02; C07H19/16; C07H21/00; C07H21/04; C07H23/00; (IPC1-7): C07H21/04; C07H21/02
Attorney, Agent or Firm:
Chika Takagi (2 outside)