【発明の名称】トランスフェクション用の新しいカチオンリン脂質

Title:

【発明の名称】トランスフェクション用の新しいカチオンリン脂質

Document Type and Number:

Japanese Patent JPH10500399

Kind Code:

A

Abstract:

A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to male.

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Inventors:

Ashley, Gary W.
McDonald, Robert Swie.
Fern, Miho

Application Number:

JP52522195A

Publication Date:

January 13, 1998

Filing Date:

March 28, 1995

Export Citation:

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Assignee:

Northwestern Universty

International Classes:

A61K9/127; C07F9/09; C07F9/10; C07F9/113; C07F9/653; C12N15/88; C12P9/00; (IPC1-7): C07F9/10; A61K9/127; C07F9/09; C07F9/10; C07F9/113; C12P9/00

Attorney, Agent or Firm:

Hidekazu Miyoshi (1 outside)

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