【発明の名称】新規生理活性物質HS―142―1およびその製造法

Title:

【発明の名称】新規生理活性物質HS―142―1およびその製造法

Document Type and Number:

Japanese Patent JP2859684

Kind Code:

B2

Abstract:

Compounds comprising a linear beta 1 -> 6 glucan esterified by caproic acid, the number of D-glucose residues being from 7 to 40 and the number of caproic acid residues being from 2 to 30, may be obtained by fermentation of a microorganism of the genus Aureobasidium. These compounds are designated HS-142-1. Preferred microorganism is Aureobasidium pullulans var. melanigenum KAC-2383 (FERM-BP 2407). The compounds of the present invention exhibit excellent antagonistic activity to ANP and are capable of inhibiting the bonding of ANP to ANP receptors.

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Inventors:

MORISHITA YOSHIKAZU
TAKAHASHI MITSURU
YAMADA KOJI
SANO TOMOYUKI
KAWAMOTO ISAO
ANDO KATSUHIKO
SANO HIROSHI
SAITO YUTAKA
KASE HIROSHI
MATSUDA YUZURU

Application Number:

JP9429590A

Publication Date:

February 17, 1999

Filing Date:

April 10, 1990

Export Citation:

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Assignee:

KYOWA HATSUKO KOGYO KK

International Classes:

A61K31/70; A61K31/7024; A61P9/02; A61P13/02; A61P15/00; C07H13/06; C08B37/00; C12P19/04; C12R1/645; (IPC1-7): C08B37/00; C12P19/04

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