Title:
【発明の名称】新規PTP20、PCP―2、BDP―1、CLK、およびSIRPタンパク質並びに関連する生成物および方法
Document Type and Number:
Japanese Patent JP2000512482
Kind Code:
A
Abstract:
Nucleic acid molecules encoding full length PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP polypeptides, portions of such nucleic acid molecules, nucleic acid vectors containing such nucleic acid molecules, recombinant cells containing such nucleic acid vectors, polypeptides purified from such recombinant cells, antibodies to such polypeptides, and methods of identifying compounds that bind such polypeptides or abrogate their interactions with natural binding partners. Methods for diagnosing abnormal conditions in an organism with PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP related molecules or compounds. PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, or SIRP polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptides, assays utilizing such polypeptides, and methods relating to all of the foregoing. Methods for treatment, diagnosis, and screening are provided for diseases related to PTP20, PCP-2, BDP1, mCLK2, mCLK3, mCLK4, and SIRP polypeptides or conditions characterized by an abnormal interaction between such a polypeptide and its binding partner.
Inventors:
Ulururich, Axel
Karytonenkov, Alexei Igorevich
Aoki, Naohit
Wong, Hong Yang
Cheng, Jeong Jun
Naylor, Oliver
Kim, Yeong Woon
Karytonenkov, Alexei Igorevich
Aoki, Naohit
Wong, Hong Yang
Cheng, Jeong Jun
Naylor, Oliver
Kim, Yeong Woon
Application Number:
JP53044097A
Publication Date:
September 26, 2000
Filing Date:
June 17, 1997
Export Citation:
Assignee:
Max-Planck-Gesellschaft Tour Felderung der Wissenschaften A Fao
International Classes:
C12N15/09; C07K14/47; C07K16/18; C07K16/40; C12N5/10; C12N9/12; C12N9/16; A61K38/00; (IPC1-7): C12N15/09; C07K14/47; C07K16/18; C07K16/40; C12N5/10; C12N9/12; C12N9/16; C12Q1/02; C12Q1/68
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)