Title:
【発明の名称】神経伝達物質放出増強薬としての新規な非環式および環式アミド類
Document Type and Number:
Japanese Patent JP3004728
Kind Code:
B2
Abstract:
PCT No. PCT/IB95/00189 Sec. 371 Date Feb. 19, 1997 Sec. 102(e) Date Feb. 19, 1997 PCT Filed Mar. 20, 1995 PCT Pub. No. WO95/29909 PCT Pub. Date Nov. 9, 1995This invention relates to compounds of formula (IA), (IB), (IC) or (ID), wherein m, X, Z, R2, R3, R4, R5, R6, R14 and the dotted lines are as defined below, their pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of using them to treat Alzheimer's disease, age-associated memory impairment, Parkinson's disease and other central nervous system disorders. The claimed compounds have the ability to enhance the release of neurotransmitters such as acetylcholine, dopamine and serotonin. (IA)
Inventors:
Volkman, Robert, A.
Jessie, Vitoutas, Jay.
Bright, Jen, M.
Villa Lobos, Anabella
Seymour, Patricia, A.
Jessie, Vitoutas, Jay.
Bright, Jen, M.
Villa Lobos, Anabella
Seymour, Patricia, A.
Application Number:
JP52808995A
Publication Date:
January 31, 2000
Filing Date:
March 20, 1995
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
A61K31/00; A61K31/215; A61K31/341; A61K31/381; A61K31/395; A61K31/415; A61K31/4164; A61K31/4166; A61K31/4178; A61K31/4192; A61K31/4196; A61K31/42; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/4427; A61K31/443; A61K31/4439; A61K31/495; C07D213/56; A61K31/4965; A61K31/497; A61K31/505; A61K31/506; A61P25/00; A61P25/16; A61P25/18; A61P25/22; A61P25/28; A61P25/30; A61P43/00; C07C233/06; C07D213/20; C07D231/12; C07D233/76; C07D239/26; C07D241/12; C07D249/04; C07D249/08; C07D261/08; C07D307/16; C07D307/54; C07D333/24; C07D401/06; C07D401/14; C07D405/06; C07D405/14; C07D413/06; (IPC1-7): C07D207/26; A61P25/18; A61P25/28; A61P43/00; A61K31/40; A61K31/4025; A61K31/4166; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/496; A61K31/506; C07D207/36; C07D207/40; C07D233/30; C07D233/66; C07D401/06; C07D401/14; C07D405/06; C07D413/06
Domestic Patent References:
| JP62277381A | ||||
| JP3118377A | ||||
| JP1207268A | ||||
| JP7503005A | ||||
| JP8503736A |
Other References:
【文献】米国特許5278162(US,A)
Attorney, Agent or Firm:
Hiroshi Kobayashi