【発明の名称】新規ピペリジン化合物、それらの製造法、およびそれらを含有する製剤組成物

Japanese Patent JP3004574

B2

Piperidine derivs. of formula (I), their isomers, quat. ammonium piperidine salts and acid addn. salts are new. R1 = 1-6C alkyl; or Ph, thienyl, pyridyl or naphthyl (all opt. substd. by one or more halo, OH, 1-6C alkoxy, 1-6C alkyl, trihalomethyl or 1-hydroxy-2,2,2-trifluoroethyl); R2 = H, 1-6C alkyl (opt. substd. by one or more 1-6C alkoxy, Ph, amino or phthalamido) or Ph (opt. substd. by one or more halo, 1-6C alkyl, 1-6C alkoxy, OH or trihalomethyl), 3-7C cycloalkyl, piperidino or amino (opt. substd. by 1-2 1-6C alkyl); X = CO or SO2; R3 = H or 1-6C alkyl; R4 = 1-6C alkyl, Ph (opt. substd. by one or more halo, 1-6C alkyl, 1-6C alkoxy, OH or trihalomethyl) or trihalomethyl; or CR3CR4 = 3-7C cycloalkenyl; and A completes a phenyl, pyridyl or naphthyl ring (all opt. substd. by one or more halo, 1-6C alkyl, 1-6C alkoxy, OH, amino, NO2 or trihalomethyl).

WO/2019/206049	HPK1 INHIBITORS, PREPARATION METHOD AND APPLICATION THEREOF
WO/1994/020467	NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME
WO/1994/008990	N-ARYLHETEROARYLALKYL 1-PHENYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS

Guillaume de Nantuil
Georges Lemond
Bernard Portovin
Jaclyn Bonne
Emmanuel Canet
Graham Burrell

JP27281995A

January 31, 2000

October 20, 1995

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Adair e Company

A61K31/4427; A61K31/445; A61P1/00; A61P11/00; A61P13/02; A61P15/00; A61P25/00; A61P25/04; A61P25/06; A61P29/00; A61P37/08; A61P43/00; C07D401/06; C07D471/04; (IPC1-7): C07D401/06; A61P1/00; A61P11/06; A61P13/00; A61P29/00; A61P37/08; A61P43/00; A61K31/454

Hajime Tsukuni (2 outside)

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