Title:
【発明の名称】ピキア(Pichia)蛋白質分解活性に影響する遺伝子およびその使用
Document Type and Number:
Japanese Patent JPH06506117
Kind Code:
A
Abstract:
The isolation and characterization of genes involved in proteolytic processing in species of the genus Pichia is described. The availability of such genes has enabled the generation of strains of Pichia which are deficient in proteolytic activity, which strains are useful as hosts for the expression of proteolytically sensitive recombinant products. The isolation and characterization of additional genes from species of the genus Pichia is also described, as well as uses therefore.
Inventors:
Gresson, Martin Anthony
Howard, Bradley Drake
Howard, Bradley Drake
Application Number:
JP50936992A
Publication Date:
July 14, 1994
Filing Date:
March 31, 1992
Export Citation:
Assignee:
Merck End Company, Inc.
International Classes:
C07K14/39; C07K14/65; C12N1/19; C12N9/48; C12N9/60; C12N9/88; C12N15/09; C12N15/57; C09K13/00; C12N15/81; C12R1/84; (IPC1-7): C12N15/57; C09K13/00; C12N1/19; C12N15/53; C12N15/60; C12N15/81
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)