Title:
【発明の名称】セリンプロテアーゼ阻害剤としてのキノロン
Document Type and Number:
Japanese Patent JP2002509928
Kind Code:
A
Abstract:
The invention discloses quinolinones which display inhibitory effects on serine proteases such as factor Xa, thrombin and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts and prodrugs of the compounds, pharmaceutically acceptable compositions comprising the compounds, their salts or prodrugs, and methods of using them a therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.
Inventors:
Dunnett Andrea Dudley
Jeremy John Edmunds
Jeremy John Edmunds
Application Number:
JP2000541167A
Publication Date:
April 02, 2002
Filing Date:
December 15, 1998
Export Citation:
Assignee:
Warner-Lambert Company
International Classes:
A61K31/4704; A61K31/4709; A61P7/02; A61P9/00; A61P43/00; C07D215/227; C07D401/06; C07D401/14; C07D403/06; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D413/14; C07D417/12; C07D417/14; C07D215/22; (IPC1-7): C07D401/06; A61K31/4704; A61K31/4709; A61P7/02; A61P9/00; A61P43/00; C07D401/14; C07D403/06; C07D405/14; C07D413/14
Attorney, Agent or Firm:
Chika Takagi (1 person outside)