Title:
【発明の名称】抗テストステロン化合物およびその使用方法
Document Type and Number:
Japanese Patent JPH06510982
Kind Code:
A
Abstract:
Compounds are provided which are highly selective inhibitors of the cytochrome P-450C17, commonly known as 17,20-lyase enzyme, responsible for androgen biosynthesis. These compounds can be administered to patients to inhibit the production of testosterone and estradiol, which is particularly valuable in the clinical treatment of prostate cancer and benign prostatic hyperplasia, as well as of uterine cancer, ovarian cancer and estradio-dependent breast cancer.
Inventors:
Wilson, Stephen, Earl.
Miao, Emily
Miao, Emily
Application Number:
JP50735992A
Publication Date:
December 08, 1994
Filing Date:
February 27, 1992
Export Citation:
Assignee:
New York University
International Classes:
A61K31/57; A61P35/00; C07J5/00; C07J31/00; C07J33/00; C07J41/00; C07J51/00; C12N9/99; (IPC1-7): C07J41/00; A61K31/57; C07J5/00; C07J31/00; C12N9/99
Attorney, Agent or Firm:
Akira Asamura (3 outside)