Title:
【発明の名称】二環式フィブリノゲン拮抗物質
Document Type and Number:
Japanese Patent JPH08505145
Kind Code:
A
Abstract:
This invention relates to compounds of formulae (I), (II), (II), wherein A<1> is O, S, N-R<1> or CHR<1>; A<4> is N-R<4> or CHR<4>; R<2> is a sidechain containing an acid or ester group; R<1>, R<4> and R<5> are substituents such as H, alkyl and aryl alkyl, and R<6> is a sidechain containing a nitrogen group; and pharmaceutically acceptable salts thereof, which are effective for inhibiting platelet aggregation, pharmaceutical compositions for effecting such activity, and a method for inhibiting platelet aggregation.
Inventors:
Bondel, William Edward
Colahan, James Francis
Huffman, William Francis
Keenan, Richard McRoch
Ku, Thomas Wenhu
Kenland Allen, Newlander
Samanen, James Martin
Eugene Skaus, Irene Nijore
Colahan, James Francis
Huffman, William Francis
Keenan, Richard McRoch
Ku, Thomas Wenhu
Kenland Allen, Newlander
Samanen, James Martin
Eugene Skaus, Irene Nijore
Application Number:
JP51538794A
Publication Date:
June 04, 1996
Filing Date:
December 21, 1993
Export Citation:
Assignee:
SMITHKLINE BEECHAM CORPORATION
International Classes:
A61K31/4409; A61K31/4418; A61K31/4427; A61K31/445; A61K31/4465; A61K31/451; A61K31/55; A61K31/551; A61P7/02; C07D211/18; C07D211/22; C07D211/26; C07D211/70; C07D213/24; C07D213/74; C07D223/16; C07D243/04; C07D243/14; C07D243/24; C07D267/14; C07D295/04; C07D295/08; C07D295/10; C07D295/12; C07D401/12; C07D401/14; C07D403/12; C07D453/02; (IPC1-7): C07D223/16; A61K31/445; A61K31/55; C07D211/22; C07D211/26; C07D211/70; C07D213/74; C07D243/04; C07D243/14; C07D295/04; C07D295/08; C07D295/10; C07D295/12; C07D401/12; C07D401/14; C07D403/12; C07D453/02
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)