Title:
【発明の名称】脂肪酸末端ポリ無水物
Document Type and Number:
Japanese Patent JP3294273
Kind Code:
B2
Abstract:
Fatty acid terminated polyanhydrides suitable for use as controlled release matrices in biodegradable sustained release drug delivery systems and methods for making thereof are described. The polymers are more soluble in organic solvents, and have a lower melting point than the corresponding non-fatty acid terminated polyanhydrides. The fatty acid terminated polyanhydrides are also more hydrophobic than the corresponding polyanhydrides that are not terminated with a fatty acid, and combine the properties of thermodynamic and hydrolytic stability, and easy storage. The polymers can be produced with a controlled and low molecular weight. The polyanhydrides are useful in a number of applications, including as a matrix in biodegradable drug delivery systems.
Inventors:
Dom, Abraham Jay.
Mania, Manoge
Mania, Manoge
Application Number:
JP50547193A
Publication Date:
June 24, 2002
Filing Date:
September 08, 1992
Export Citation:
Assignee:
Massachusetts Institute of Technology
International Classes:
A61K9/22; A61K6/00; A61K9/20; A61K47/30; A61K47/48; A61L31/06; A61L31/16; C08G63/00; C08G67/00; C08G67/04; C08G69/10; C08G69/48; (IPC1-7): C08G67/04; A61K9/22; A61K47/30; C08G63/00; C08G69/10; C08G69/48
Domestic Patent References:
| JP6291527A |
Attorney, Agent or Firm:
Shusaku Yamamoto