Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
【発明の名称】HTLV-▲III▼抗体の診断用ペプチド並びにそれらの製造法及び用途
Document Type and Number:
Japanese Patent JP2733059
Kind Code:
B2
Abstract:
A process for recovering recombinant protein from refractile inclusion bodies of microorganisms comprises disrupting cells, recovering refractile bodies containing recombinant protein, solubilizing the refractile bodies with a denaturant, protecting sulfhydryl groups of recombinant proteins, converting cationic amino groups of recombinant proteins to anionic carboxylic acid by derivatization with organic cyclic acid anhydrides, and recovering recombinant protein derivatives. Solid supports may be coated with recombinant protein recovered by the above process, and such supports may be used for the detection and quantification of antibodies to the recombinant proteins in body fluids.

Inventors:
BERUTSU JERARUDO EE
SOON RICHAADO EMU
MARUCHIAANI DANTE JUAN
FUN CHUNNHO
HAZERUTAIN UIRIAMU EE
Application Number:
JP50154687A
Publication Date:
March 30, 1998
Filing Date:
February 03, 1987
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KENBURITSUJI BAIOSAIENSU CORP
International Classes:
A61K39/21; C07H21/02; C07K1/107; C07K1/113; G01N33/53; C07K1/14; C07K1/16; C07K14/00; C07K14/15; C07K14/155; C07K14/16; C07K16/00; C07K16/10; C07K19/00; C08F8/42; C12N7/04; C12N15/09; C12N15/12; C12P21/00; C12P21/02; C12P21/08; C12Q1/68; G01N33/531; G01N33/536; G01N33/543; G01N33/569; G01N33/577; A61K38/00; C12R1/19; (IPC1-7): C07K14/155; G01N33/569
Other References:
Cell,Vol.41 (1985−Jul) P.979−986
Nature,Vol.313 (1985−Jan) P.277−284
Nature,Vol.315 (1985−May) P.151−154
Attorney, Agent or Firm:
Kazuo Sato (2 outside)